Matrix phase fractionation: Investigating the compromise between dynamic range of analyte extraction and spatial resolution in mass spectrometry imaging.
Matthew B O'RourkeBarney ViengkhouCaine C SmithLorenz SondereggerMatthew P PadulaGreg T SutherlandMarkus J HoferBen CrossettPublished in: Rapid communications in mass spectrometry : RCM (2021)
We have found that, by utilising matrix phase fractionation for the detection of lipids in brain tissue, it is possible to create a significantly more comprehensive dataset than would otherwise be possible with traditional 'single-run' workflows.