Adult granulosa cell tumors of the ovary: a retrospective study of 30 cases with respect to the expression of steroid synthesis enzymes.
Sachiko KitamuraKaoru AbikoNoriomi MatsumuraHidekatsu NakaiYumiko AkimotoHirotoshi TanimotoIkuo KonishiPublished in: Journal of gynecologic oncology (2018)
The expression of hormone-synthesizing enzymes divides granulosa cell tumors into 2 distinct types; tumors with P450c17-positive cells show elevated serum Eā and related clinical symptoms, while tumors without these cells show symptoms related to FSH suppression by inhibin.
Keyphrases
- induced apoptosis
- poor prognosis
- cell cycle arrest
- single cell
- cell therapy
- polycystic ovary syndrome
- signaling pathway
- endoplasmic reticulum stress
- cell death
- binding protein
- type diabetes
- stem cells
- adipose tissue
- mesenchymal stem cells
- skeletal muscle
- long non coding rna
- insulin resistance
- cell proliferation
- depressive symptoms
- drug induced