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Establishment of novel immortalized middle ear cell lines as models for otitis media.

Simon Blaine-SauerTina L SamuelsPawjai KhampangKe YanMichael E McCormickRobert H ChunSteven A HarveyDavid R FriedlandNikki JohnstonJoseph E Kerschner
Published in: Laryngoscope investigative otolaryngology (2023)
Immortalized MEE lines retained the inflammatory expression and responsiveness of their tissues of origin and differences between non-OM versus OM and pediatric versus adult cultures, supporting their value as novel in vitro culture models for OM.
Keyphrases
  • poor prognosis
  • oxidative stress