DNMT1 involved in the analgesic effect of folic acid on gastric hypersensitivity through downregulating ASIC1 in adult offspring rats with prenatal maternal stress.
Hong-Jun WangFu-Chao ZhangTimothy W XuYu-Cheng XuYuan-Qing TianYan-Yan WuJi-Tian XuShufen HuGuang-Yin XuPublished in: CNS neuroscience & therapeutics (2023)
These results indicate that increased DNMT1 contributes to the analgesic effect of FA on PMS-induced GHS by reducing ASIC1 expression and sensitivity.