Endometrial Cancer Risk in Women With Germline BRCA1 or BRCA2 Mutations: Multicenter Cohort Study.
Marthe M de JongeCornelis D de KroonDenise J JennerJan OostingJoanne A de HulluMarian J E MouritsEncarna B Gómez GarciaMargreet G E M AusemsJ Margriet ColléeKlaartje van EngelenIrma van de Beeknull nullVincent T H B M SmitMatti A RookusGeertruida H de BockFlora E van LeeuwenTjalling BosseOlaf M DekkersChristi J van AsperenPublished in: Journal of the National Cancer Institute (2022)
BRCA1/2 mutation carriers have a two- to threefold increased risk for EC, with highest risk observed for the rare subgroups of serous-like and p53-abnormal EC in BRCA1 mutation carriers.