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BRAF V600E promotes DC3/monocyte differentiation in human gene-engineered HSPCs and causes multisystem histiocytosis.

Tommaso SconocchiaJohannes FoßeltederLisa AuingerErdem ÖzkayaTheresa BenezederMagdalena LangChristine Beham-SchmidGerald HoeflerArmin ZebischAlbert WölflerHeinz SillPeter WolfHerbert StroblAndreas Reinisch
Published in: Leukemia (2023)
Keyphrases
  • endothelial cells
  • dendritic cells
  • induced pluripotent stem cells
  • copy number
  • genome wide
  • pluripotent stem cells
  • peripheral blood
  • immune response
  • gene expression