Acute seizure risk in patients with encephalitis: development and validation of clinical prediction models from two independent prospective multicentre cohorts.
Greta K WoodRoshan BabarMark A EllulRhys Huw ThomasHarriet Van Den ToorenAva EastonKukatharmini TharmaratnamGirvan BurnsideAli M AlamHannah CastellSarah BoardmanCeryce CollieBethany FacerCordelia DunaiSylviane DefresJulia GranerodDavid W G BrownAngela VincentAnthony Guy MarsonSarosh R IraniTom SolomonBenedict D MichaelPublished in: BMJ neurology open (2022)
Age, GCS, fever and aetiology can effectively stratify acute seizure risk in patients with encephalitis. These findings can support the development of targeted interventions and aid clinical trial design for antiseizure medication prophylaxis.
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