Antimicrobial photodynamic therapy with methylene blue and its derivatives in animal studies: Systematic review.

Ana Paula Martin CardozoDaniela de Fátima Teixeira da SilvaKristianne Porta Santos FernandesRita de Cassia FerreiraAdriana Lino-Dos-Santos-FrancoMaria Fernanda Setúbal Destro RodriguesLara Jansiski MottaRebeca Boltes Cecatto

Published in: Photodermatology, photoimmunology & photomedicine (2024)

MB is a safe and promising agent used as a photosensitizer in aPDT for skin-infected lesions. There is great variability in the parameters found. Comparisons concerning concentration, irradiation time, and light intensity need to be performed.

Keyphrases

photodynamic therapy
systematic review
fluorescence imaging
meta analyses
staphylococcus aureus
high intensity
soft tissue
randomized controlled trial
wound healing
radiation induced
structure activity relationship