Efficacy and effectiveness of high-dose versus standard-dose influenza vaccination for older adults: a systematic review and meta-analysis.

Jason K H LeeGary K L LamThomas ShinJiyeon KimAnish KrishnanDavid P GreenbergAyman Chit

Published in: Expert review of vaccines (2018)

Available evidence suggests HD-IIV3 is more effective than SD-IIV3 at reducing the clinical outcomes associated with influenza infection in older adults and should be considered for routine use in the 65+ population.

Keyphrases

high dose
physical activity
randomized controlled trial
low dose
systematic review
stem cell transplantation
clinical practice