Rubicon can predict prognosis in patients with pancreatic ductal adenocarcinoma after neoadjuvant chemoradiotherapy.

Daiki MarukawaKunihito GotohShogo KobayashiKazuki SasakiYoshifumi IwagamiDaisaku YamadaYoshito TomimaruHirofumi AkitaTadafumi AsaokaTakehiro NodaHidenori TakahashiMasahiro TanemuraYuichiro DokiHidetoshi Eguchi

Published in: International journal of clinical oncology (2023)

High Rubicon expression is a significant, unfavorable prognostic factor in pancreatic ductal adenocarcinoma after neoadjuvant chemoradiotherapy. Downregulation of Rubicon expression improves invasion ability and cell viability in gemcitabine-resistant pancreatic ductal adenocarcinoma.

Keyphrases

locally advanced
rectal cancer
prognostic factors
poor prognosis
squamous cell carcinoma
radiation therapy
lymph node
binding protein
signaling pathway
cell proliferation
long non coding rna
cell migration