[Covalently conjugated DNA aptamer with doxorubicin as in vitro model for effective targeted drug delivery to human glioblastoma tumor cells].
Ya A SlimanN S SamoylenkovaO A AntipovaVladimir A BrylevD A VeryutinKsenia A SapozhnikovaA I AlekseevaI N ProninAlexey M KopylovGalina Valerievna PavlovaPublished in: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko (2024)
We established obvious antiproliferative effect of covalent conjugate DOX-GR20 on continuous human glioblastoma cell culture Sus/fP2 without toxic effect on the reference culture (dermal fibroblasts DF1).