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Lactobacillus gallinarum -derived metabolites boost anti-PD1 efficacy in colorectal cancer by inhibiting regulatory T cells through modulating IDO1/Kyn/AHR axis.

Winnie FongQing LiFenfen JiWei LiangHarry Cheuk Hay LauXing KangWeixin LiuKenneth Kin-Wah ToZhong ZuoXiao-Xing LiXiang ZhangJoseph Jao Yiu SungJun Yu
Published in: Gut (2023)
is a potential adjuvant to augment anti-PD1 efficacy against CRC.
Keyphrases
  • regulatory t cells
  • signaling pathway
  • dendritic cells
  • early stage
  • ms ms