Organ and cell-specific biomarkers of Long-COVID identified with targeted proteomics and machine learning.
Maitray A PatelMichael J KnauerMichael NicholsonMark DaleyLogan R Van NynattenGediminas CepinskasDouglas D FraserPublished in: Molecular medicine (Cambridge, Mass.) (2023)
Proteomic analysis of plasma from Long-COVID patients identified 119 highly relevant proteins and two optimal models with nine and five proteins, respectively. The identified proteins reflected widespread organ and cell type expression. Optimal protein models, as well as individual proteins, hold the potential for accurate diagnosis of Long-COVID and targeted therapeutics.