Disgust is an emotion that regulates disease avoidance and reduces the likelihood of pathogenic infections. Existing research suggests a bidirectional relationship between disgust and mating, where disgust inhibits sexual behavior and sexual behavior inhibits disgust. In the current study, we investigated the role of individual differences and mating motivations on visual attention to pathogenic cues. Participants ( N = 103) were randomly assigned to a mating prime or control condition, and they were asked to view images of pathogenic cues (i.e., rotten food, exposed cuts, bodily fluids) paired with their non-pathogenic counterparts. The findings showed no effect of mating prime on visual attention to pathogenic stimuli; however, dispositional mating strategies (SOI-R) were associated with attention to pathogenic stimuli. Individuals with unrestricted sociosexual orientations viewed pathogenic stimuli longer. The findings demonstrate that dispositional mating orientation is associated with greater attention to disgusting images, a link between pathogens and mating orientation that warrants further exploration.