Reactivation of rolB transgene expression in Vitis amurensis Rupr. cells upon retransformation with 2b gene from Cucumovirus isolate NK.

Alexey P TyuninNikolay N NityagovskyYuri A KaretinKonstantin V Kiselev

Published in: Biotechnology letters (2019)

2b from CMV-NK can reactivate a silenced transgene expression, even after 10 years of subcultivation, nevertheless, optimization of the methods concerning 2b introduction in plant genomes is necessary to avoid undesirable silencing effects.

Keyphrases

poor prognosis
induced apoptosis
cell cycle arrest
binding protein
nk cells
long non coding rna
copy number
genome wide
gene expression
cell death
oxidative stress
signaling pathway