Systematic review of atypical hemolytic uremic syndrome biomarkers.
Rupesh RainaSidharth K SethiMarie-Agnès Dragon-DureyAmrit KhooblallDivya SharmaPriyanka KhandelwalRon ShapiroOlivia BoyerHui Kim YapArvind BaggaChristoph LichtPublished in: Pediatric nephrology (Berlin, Germany) (2022)
If a comprehensive complement profile were built using our data, aHUS would be identified by low levels of C3, CH50, AH50, and CFB along with increased levels of C5a, C5b-9, Bb, anti-CFH autoantibodies, and D-dimer. A higher resolution version of the Graphical abstract is available as Supplementary information.