Comparison of intranasal versus intravenous midazolam for management of status epilepticus in dogs: A multi-center randomized parallel group clinical study.

Marios CharalambousHolger A VolkAndrea TipoldJohannes ErathEnrice HuenerfauthAntonella GallucciGualtiero GandiniDaisuke HasegawaTheresa PancottoJohn H RossmeislSimon PlattLuisa De RisioJoan R CoatesMihai MusteataFederica TirritoFrancesca CozziLaura PorcarelliDaniele CorlazzoliRodolfo CappelloAn VanhaesebrouckBart J G BroeckxLuc Van HamSofie F M Bhatti

Published in: Journal of veterinary internal medicine (2019)

Both routes are quick, safe, and effective for controlling status epilepticus. However, the IN route demonstrated superiority when the time needed to place an IV catheter was taken into account.

Keyphrases

double blind
placebo controlled
open label
phase iii
clinical trial
high dose
phase ii
study protocol
randomized controlled trial
clinical evaluation