Kidney biopsy findings in children with sickle cell disease: a Midwest Pediatric Nephrology Consortium study.

Rima S ZahrMarianne E YeeJack WeaverKatherine TwombleyRaed Bou MatarDiego AvilesRajasree SreedharanMichelle N RheaultRossana Malatesta-MuncherHillarey StoneTarak SrivastavaGaurav KapurPoornima BaddiOded VolovelskyJonathan PelletierRasheed GbadegesinWacharee SeeherunvongHiren P PatelLarry A Greenbaum

Published in: Pediatric nephrology (Berlin, Germany) (2019)

Renal biopsies, while not commonly performed in children with SCD, were universally abnormal. Outcomes were poor in this cohort of patients despite a variety of post-biopsy interventions. Effective early intervention to prevent chronic kidney disease (CKD) is needed to reduce morbidity and mortality in children with SCD.

Keyphrases

chronic kidney disease
end stage renal disease
young adults
ultrasound guided
randomized controlled trial
peritoneal dialysis
newly diagnosed
physical activity
type diabetes
skeletal muscle