Lnc-GULP1-2:1 affects granulosa cell proliferation by regulating COL3A1 expression and localization.

Guidong YaoYue KongGuang YangDeqi KongYijiang XuJiahuan HeZiwen XuYucheng BaiHuiying FanQina HeYingpu Sun

Published in: Journal of ovarian research (2021)

Lnc-GULP1-2:1 affects the proliferation of granulosa cells by regulating the expression and localization of COL3A1 protein, and may participate in the regulation of ovarian follicle development. This study will provide new insight into molecular mechanisms underlying ovarian follicular development, which will help generate novel diagnostic and therapeutic strategies for diseases related to ovarian follicular development disorders.

Keyphrases

cell proliferation
poor prognosis
binding protein
cell cycle
cell cycle arrest
skeletal muscle
protein protein