Oxylipin Dynamics Following A Single Bout of Yoga Exercise: A Pilot Randomized Controlled Trial Secondary Analysis.
Dennis Muñoz-VergaraPamela M RistEunMee YangGloria Y YehNorman LeePeter M WaynePublished in: Journal of integrative and complementary medicine (2024)
Background: Yoga may promote health via a complex modulation of inflammation. Little is known about oxylipins, a class of circulating mediators involved in inflammation resolution. Objective: To explore the acute effects of yoga exercise on systemic levels of oxylipins. Methods: This is a secondary analysis of a three-arm (high-intensity-yoga: HY, n = 10); moderate-intensity-yoga: MY, n = 10; and no-intervention-control: CON, n = 10) pilot randomized controlled trial employing a single bout of yoga exercise. Blood samples (baseline and 4-timepoint post-intervention) were used for an unbiased metabolipidomic profiling analysis. Net Areas Under the Curve per oxylipin were evaluated for each group. Results: Lipoxin(LX)B4, prostaglandin(PG)D2, and resolvin(Rv)D3 exhibited a greater magnitude of change in HY compared with MY and CON. Conclusion: Findings inform the design of future trials exploring the acute effects of yoga exercise on oxylipins' systemic levels.
Keyphrases
- high intensity
- randomized controlled trial
- resistance training
- study protocol
- oxidative stress
- liver failure
- healthcare
- physical activity
- mycobacterium tuberculosis
- public health
- drug induced
- respiratory failure
- systematic review
- clinical trial
- mental health
- risk assessment
- health information
- aortic dissection
- body composition
- climate change
- current status
- single molecule
- hepatitis b virus