Interference chromatography: a novel approach to optimizing chromatographic selectivity and separation performance for virus purification.

Lisa A SantryRenaud JacquemartMelissa VandersluisMochao ZhaoJake M DommThomas M McAuslandXiaojiao ShangPierre M MajorJames G StoutSarah K Wootton

Published in: BMC biotechnology (2020)

When used in conjunction with membrane chromatography, this high yield method based on interference chromatography has the potential to deliver efficient, scalable processes to enable viable production of oncolytic virotherapies.

Keyphrases

liquid chromatography
mass spectrometry
high speed
tandem mass spectrometry
high performance liquid chromatography
simultaneous determination
high resolution
solid phase extraction
climate change