DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis.

Qian LiuAnping LiShengnan YuShuang QinNa HanRichard G PestellXinwei HanKongming Wu

Published in: Journal of hematology & oncology (2018)

Our study proved that CXCL8 acted as an unfavorable factor promoting to tumor progression and poor prognosis of ADC, while DACH1 antagonized CXCL8 to provide a favorable survival of ADC patients. Double detection of DACH1 and CXCL8 may provide a precise information for further evaluating the prognosis of ADC patients.

Keyphrases

poor prognosis
end stage renal disease
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
healthcare
magnetic resonance imaging
diffusion weighted imaging
quantum dots