Macrophage activation syndrome in pediatrics: 10 years data from an Indian center.
Priyankar PalJigna BathiaPrabhas Prasun GiriMandira RoyAlolika NandiPublished in: International journal of rheumatic diseases (2020)
Macrophage activation syndrome is a near fatal complication with protean manifestations and multiorgan dysfunction. Hyperferritinemia is characteristic, higher values being associated with increased mortality. Cases resistant to steroids and cyclosporine had a poor prognosis. Late presentations with multiorgan dysfunction were associated with the poorest outcomes.