Incorporating data from multiple endpoints in the analysis of clinical trials: example from RSV vaccines.

Ottavia PrunasJoukje E WillemsenLouis BontVirginia E PitzerJoshua L WarrenDaniel M Weinberger

Published in: Epidemiology (Cambridge, Mass.) (2023)

Analyzing multiple endpoints using a weighted permutation method can increase power while controlling the type I error rate compared to established methods under conditions mirroring real-world RSV clinical trials.

Keyphrases

clinical trial
respiratory syncytial virus
respiratory tract
phase ii
magnetic resonance
open label
big data
double blind
study protocol
phase iii
computed tomography
randomized controlled trial
network analysis
contrast enhanced