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Intra- and Inter-host Evolution of Human Norovirus in Healthy Adults.

Sasirekha RamaniSara J Javornik CregeenAnil SurathuFrederick H NeillDonna M MuznyHarsha DoddapaneniVipin K MenonKristi L HoffmanMatthew C RossGinger A MetcalfAntone R OpekunDavid Y GrahamRichard A GibbsJoseph F PetrosinoMary K EstesRobert L Atmar
Published in: bioRxiv : the preprint server for biology (2024)
These data highlight the potential of a new capture-based sequencing approach to assemble human norovirus genomes with high sensitivity and demonstrate limited conserved immune pressure-driven evolution of GI.1 virus in healthy adults.
Keyphrases
  • endothelial cells
  • pluripotent stem cells
  • transcription factor
  • electronic health record
  • machine learning
  • deep learning