Intra- and Inter-host Evolution of Human Norovirus in Healthy Adults.
Sasirekha RamaniSara J Javornik CregeenAnil SurathuFrederick H NeillDonna M MuznyHarsha DoddapaneniVipin K MenonKristi L HoffmanMatthew C RossGinger A MetcalfAntone R OpekunDavid Y GrahamRichard A GibbsJoseph F PetrosinoMary K EstesRobert L AtmarPublished in: bioRxiv : the preprint server for biology (2024)
These data highlight the potential of a new capture-based sequencing approach to assemble human norovirus genomes with high sensitivity and demonstrate limited conserved immune pressure-driven evolution of GI.1 virus in healthy adults.