Asterosaponins from the starfish Protoreaster nodosus .
Le Thi VienTran Thi Hong HanhTran Hong QuangNguyen Van ThanhNguyen Xuan CuongNguyen Hoai NamThung Do CongPhan Van KiemPublished in: Journal of Asian natural products research (2023)
Five asterosaponins ( 1 - 5 ), including one new compound named protonodososide ( 1 ), were isolated from the methanol extract of the starfish Protoreaster nodosus , after subjecting to various chromatographic separations. The structural elucidation was confirmed by careful analysis of the 1D, 2D NMR, and HR ESI QTOF mass spectra. The cytotoxicity of isolated compounds was evaluated on five human cancer cell lines including HepG2, KB, MCF7, LNCaP, and SK-Mel2.
Keyphrases
- ms ms
- endothelial cells
- papillary thyroid
- magnetic resonance
- squamous cell
- induced pluripotent stem cells
- breast cancer cells
- high resolution
- simultaneous determination
- pluripotent stem cells
- squamous cell carcinoma
- mass spectrometry
- capillary electrophoresis
- density functional theory
- carbon dioxide
- childhood cancer