Clinical values of expression signature of circCDR1AS and circHIAT1 in prostate cancer: Two circRNAs with regulatory function in androgen receptor (AR) and PI3K/AKT signaling pathways.

Mahsa Aghajani MirHossein DinmohammadiEmadoddin MoudiNima MotamedAbdolreza Daraei

Published in: Journal of clinical laboratory analysis (2022)

These observations suggest that the abnormal expression of circCDR1AS and circHIAT1 can be regarded as two different types of molecular pathology with potential biomarker values for PCa, although further studies are needed.

Keyphrases

pi k akt
signaling pathway
prostate cancer
poor prognosis
cell proliferation
cell cycle arrest
binding protein
transcription factor
epithelial mesenchymal transition