Polymer-free drug-coated vs. bare-metal coronary stents in patients undergoing non-cardiac surgery: a subgroup analysis of the LEADERS FREE trial.
Gert RichardtMohammad AbdelghaniAbdelhakim AllaliRalph ToelgMohamed AbdellaouiFlorian KrackhardtRune WisethMarie-Claude MoriceSamuel CoptHans-Peter StollPhilip UrbanPublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2020)
Among patients undergoing NCS after PCI, DCS-treated patients had a lower probability of clinically driven TLR compared with BMS. However, there was no significant difference in the occurrence of the primary composite safety end point or bleeding complications. Early NCS after BMS-PCI was associated with impaired safety, while the timing of NCS had no such influence after DCS implantation.
Keyphrases
- patients undergoing
- coronary artery disease
- cardiac surgery
- percutaneous coronary intervention
- end stage renal disease
- newly diagnosed
- atrial fibrillation
- acute coronary syndrome
- acute myocardial infarction
- ejection fraction
- coronary artery
- acute kidney injury
- clinical trial
- antiplatelet therapy
- st segment elevation myocardial infarction
- inflammatory response
- risk assessment
- phase iii
- prognostic factors
- immune response
- study protocol
- peritoneal dialysis
- randomized controlled trial
- phase ii
- risk factors
- aortic stenosis
- patient reported outcomes
- adverse drug
- aortic valve
- transcatheter aortic valve replacement
- open label