Gut microbiota maturation during early human life induces enterocyte proliferation via microbial metabolites.
Michael W DoughertyOleksandr KudinMarcus MühlbauerJosef NeuRaad Z GharaibehChristian JobinPublished in: BMC microbiology (2020)
Our findings indicate that microbial metabolites from the more diverse gut microbiome associated with pre-term infants facilitate stem cell proliferation. Therefore, perturbations of the pre-term microbiota may impair intestinal homeostasis.