Next-generation Multi-target Stool DNA Panel Accurately Detects Colorectal Cancer and Advanced Precancerous Lesions.
Zubin D GagratMartin KrockenbergerAbhik BhattacharyaBridget Z GagratChristine M LeducMichael B MatterKeith D FourrierDouglas W MahoneyDavid K Edwards VGraham P LidgardPaul J LimburgScott C JohnsonMichael J DomanicoJohn B KisielPublished in: Cancer prevention research (Philadelphia, Pa.) (2024)
This study highlights performance of the next-generation mt-sDNA test, which exhibits high sensitivity and specificity for detecting colorectal cancer and APLs. This noninvasive option has potential to increase screening participation and clinical outcomes. A multi-center, clinical validation trial is underway. See related commentary by Bresalier, p. 93.