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Fasudil hydrochloride and ozagrel sodium combination therapy for patients with aneurysmal subarachnoid hemorrhage: a cross-sectional study using a nationwide inpatient database.

Hiroshi MagaraTakuaki TaniShinobu ImaiAnna KiyomiKiyohide FushimiMunetoshi Sugiura
Published in: Journal of pharmaceutical health care and sciences (2024)
Fasudil hydrochloride and ozagrel sodium had different mechanisms of action, suggesting a synergistic effect of combination therapy. However, a comparison of fasudil hydrochloride monotherapy and combination therapy of fasudil hydrochloride and ozagrel sodium showed no difference in the prognostic effect. Therefore, it was suggested that fasudil hydrochloride monotherapy may be sufficient.
Keyphrases
  • combination therapy
  • palliative care
  • mental health
  • randomized controlled trial
  • acute care
  • electronic health record