Effects of FODMAPs and Gluten on Gut Microbiota and Their Association with the Metabolome in Irritable Bowel Syndrome: A Double-Blind, Randomized, Cross-Over Intervention Study.

Elise Nordin Per M HellströmJohan DicksvedErik PelveRikard LandbergCarl Brunius

Published in: Nutrients (2023)

FODMAPs, but not gluten, altered microbiota composition and correlated with phenolic-derived metabolites and 3-indolepropionate, with only weak associations with IBS symptoms. Thus, the minor effect of FODMAPs on IBS symptoms must be weighed against the effect on microbiota and metabolites related to positive health factors.

Keyphrases

irritable bowel syndrome
ms ms
randomized controlled trial
healthcare
public health
double blind
open label
mental health
sleep quality
placebo controlled
health information
phase iii
phase ii