Resveratrol, Epigallocatechin Gallate and Curcumin for Cancer Therapy: Challenges from Their Pro-Apoptotic Properties.
Adele ChimentoMaria D'AmicoArianna De LucaFrancesca Luisa ConfortiVincenzo PezziFrancesca De AmicisPublished in: Life (Basel, Switzerland) (2023)
Plant-derived bioactive compounds are gaining wide attention for their multiple health-promoting activities and in particular for their anti-cancer properties. Several studies have highlighted how they can prevent cancer initiation and progression, improve the effectiveness of chemotherapy, and, in some cases, limit some of the side effects of chemotherapy agents. In this paper, we provide an update of the literature on the anti-cancer effects of three extensively studied plant-derived compounds, namely resveratrol, epigallocatechin gallate, and curcumin, with a special focus on the anti-cancer molecular mechanisms inducing apoptosis in the major types of cancers globally.
Keyphrases
- cancer therapy
- cell death
- systematic review
- locally advanced
- public health
- healthcare
- papillary thyroid
- anti inflammatory
- oxidative stress
- randomized controlled trial
- drug delivery
- mental health
- endoplasmic reticulum stress
- multidrug resistant
- cell cycle arrest
- squamous cell
- squamous cell carcinoma
- radiation therapy
- cell proliferation
- risk assessment
- health promotion