First-line single-agent regorafenib in frail patients with metastatic colorectal cancer: a pilot phase II study of the Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD).

Alfredo CarratoM BenavidesB MassutíR Ferreiro-MonteagudoP García AlfonsoE FalcóM ReboredoT CanoJ GallegoJ M ViéitezL LayosA SaludE PoloE DotorG Durán-OgallaM Rodriguez-GarroteA CalvoE GrandeE Aranda

Published in: BMC cancer (2019)

This trial was prospectively registered at EudraCT ( 2013-000236-94 ). Date of trial registration: April 9th, 2013.

Keyphrases

metastatic colorectal cancer
phase ii study
study protocol
open label
phase iii
phase ii
clinical trial
locally advanced
randomized controlled trial
placebo controlled
squamous cell carcinoma
combination therapy
double blind
replacement therapy