Antiviral Effect of Hyunggaeyungyo-Tang on A549 Cells Infected with Human Coronavirus.

Seo-Young Won In-Chan Seol Ho-Ryong Yoo Yoon-Sik Kim

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

Through the reduction of the amount of coronavirus RNA, our research indicates that HGYGT has antiviral effects. The reduction of IKK and iNOS mRNA levels indicate that HGYGT reduces coronavirus RNA expression and may inhibit the replication of coronavirus by acting on NF-kB/Rel pathways to protect oxidative injury. In addition, decreases in mRNA expression levels of proinflammatory cytokines indicate that the HGYGT may relieve the symptoms of coronavirus infections.

Keyphrases

sars cov
respiratory syndrome coronavirus
induced apoptosis
signaling pathway
poor prognosis
oxidative stress
lps induced
binding protein
coronavirus disease
nuclear factor
endoplasmic reticulum stress
toll like receptor