Significant haemoglobinopathies: A guideline for screening and diagnosis: A British Society for Haematology Guideline: A British Society for Haematology Guideline.
BarbaraJ J BainYvonne DanielJoan HenthornBarbara de la SalleAmanda HoganNoémi B A RoyCiaran MooneyLisa LangabeerDavid C Reesnull nullPublished in: British journal of haematology (2023)
Antenatal screening/testing of pregnant women should be carried out according to the guidelines of the National Health Service (NHS) Sickle Cell and Thalassaemia Screening Programme. Newborn screening and, when necessary, follow-up testing and referral, should be carried out according to the guidelines of the NHS Sickle Cell and Thalassaemia Screening Programme. All babies under 1 year of age arriving in the United Kingdom should be offered screening for sickle cell disease (SCD). Preoperative screening for SCD should be carried out in patients from ethnic groups in which there is a significant prevalence of the condition. Emergency screening with a sickle solubility test must always be followed by definitive analysis. Laboratories performing antenatal screening should utilise methods that are capable of detecting significant variants and are capable of quantitating haemoglobins A 2 and F at the cut-off points required by the national antenatal screening programme. The laboratory must ensure a provisional report is available for antenatal patients within three working days from sample receipt.
Keyphrases
- pregnant women
- end stage renal disease
- emergency department
- healthcare
- chronic kidney disease
- ejection fraction
- randomized controlled trial
- squamous cell carcinoma
- study protocol
- clinical trial
- radiation therapy
- copy number
- patient safety
- gene expression
- public health
- patients undergoing
- newly diagnosed
- peritoneal dialysis