Natural history of ROHHAD syndrome: development of severe insulin resistance and fatty liver disease over time.

Abdel Wahab Jalal EldinDilara TombayogluLaura ButzAlison AffinatiRasimcan MeralMehmet Selman OntanKelly WalkovichMaria WesterhoffJeffrey W InnisNeehar D ParikhElif Arioglu Oral

Published in: Clinical diabetes and endocrinology (2019)

Metabolic abnormalities, Insulin resistance and fatty liver disease are potentially part of the ROHHAD syndrome that may develop over time. GLP1 agonists were reasonably effective to treat insulin resistance and hyperphagia. Patients with ROHHAD may benefit from close follow up in regards to liver disease.

Keyphrases

insulin resistance
adipose tissue
high fat diet
metabolic syndrome
skeletal muscle
polycystic ovary syndrome
type diabetes
high fat diet induced
case report
fatty acid