A framework for transcriptome-wide association studies in breast cancer in diverse study populations.

Arjun BhattacharyaMontserrat García-ClosasAndrew F OlshanCharles M PerouMelissa A TroesterMichael I Love

Published in: Genome biology (2020)

We show that carefully implemented and thoroughly validated TWAS is an efficient approach for understanding the genetics underpinning breast cancer outcomes in diverse populations.

Keyphrases

gene expression
single cell
rna seq
genome wide
genetic diversity
type diabetes
case control
young adults
skeletal muscle
weight loss
childhood cancer