Streptomyces alleviate abiotic stress in plant by producing pteridic acids.
Zhijie YangYijun QiaoNaga Charan KonakallaEmil StrøbechPernille HarrisGundela PeschelMiriam Agler-RosenbaumTilmann WeberErik AndreassonLing DingPublished in: Nature communications (2023)
Soil microbiota can confer fitness advantages to plants and increase crop resilience to drought and other abiotic stressors. However, there is little evidence on the mechanisms correlating a microbial trait with plant abiotic stress tolerance. Here, we report that Streptomyces effectively alleviate drought and salinity stress by producing spiroketal polyketide pteridic acid H (1) and its isomer F (2), both of which promote root growth in Arabidopsis at a concentration of 1.3 nM under abiotic stress. Transcriptomics profiles show increased expression of multiple stress responsive genes in Arabidopsis seedlings after pteridic acids treatment. We confirm in vivo a bifunctional biosynthetic gene cluster for pteridic acids and antimicrobial elaiophylin production. We propose it is mainly disseminated by vertical transmission and is geographically distributed in various environments. This discovery reveals a perspective for understanding plant-Streptomyces interactions and provides a promising approach for utilising beneficial Streptomyces and their secondary metabolites in agriculture to mitigate the detrimental effects of climate change.
Keyphrases
- climate change
- arabidopsis thaliana
- genome wide identification
- plant growth
- genome wide
- transcription factor
- stress induced
- heat stress
- microbial community
- staphylococcus aureus
- cell wall
- single cell
- dna methylation
- human health
- depressive symptoms
- high throughput
- cancer therapy
- drug delivery
- genome wide analysis
- social support