Ficoll-hypaque separation vs whole blood lysis: Comparison of efficiency and impact on minimal residual disease analysis.
Elisa GenuardiD BarberoI DogliottiB MantoanD DrandiM GambellaG M ZaccariaL MonitilloIrene Della StarzaM CavalliL A De NoviE CiabattiS GrassiA GazzolaC MannuI Del GiudiceS GalimbertiC AgostinelliP P PiccalugaM LadettoS Ferreronull nullPublished in: International journal of laboratory hematology (2017)
Based on these results, the FIL MRD Network suggests to optimize the pre-analytical phases introducing RBL approach for cell recovery in the clinical trials including MRD analysis.