Surfactant protein A promotes atherosclerosis through mediating macrophage foam cell formation.

Skylar D King Dunpeng CaiMikayla M FraunfelderShi-You Chen

Published in: bioRxiv : the preprint server for biology (2023)

Our results elucidate that SPA is a novel factor for atherosclerosis development. SPA enhances macrophage foam cell formation and atherosclerosis through increasing scavenger receptor cluster of differentiation antigen 36 (CD36) expression.

Keyphrases

cardiovascular disease
single cell
cell therapy
adipose tissue
binding protein
poor prognosis
stem cells
mesenchymal stem cells
long non coding rna
amino acid