Atherosclerosis in HIV Patients: What Do We Know so Far?
Anastasia V PoznyakEvgeny E BezsonovEvgeny E BorisovAndrey V GrechkoAndrey G KartuesovAlexander N OrekhovPublished in: International journal of molecular sciences (2022)
For the past several decades, humanity has been dealing with HIV. This disease is one of the biggest global health problems. Fortunately, modern antiretroviral therapy allows patients to manage the disease, improving their quality of life and their life expectancy. In addition, the use of these drugs makes it possible to reduce the risk of transmission of the virus to almost zero. Atherosclerosis is another serious pathology that leads to severe health problems, including disability and, often, the death of the patient. An effective treatment for atherosclerosis has not yet been developed. Both types of immune response, innate and adaptive, are important components of the pathogenesis of this disease. In this regard, the peculiarities of the development of atherosclerosis in HIV carriers are of particular scientific interest. In this review, we have tried to summarize the data on atherosclerosis and its development in HIV carriers. We also looked at the classic therapeutic methods and their features concerning the concomitant diagnosis.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv aids
- immune response
- hiv testing
- cardiovascular disease
- end stage renal disease
- hiv infected patients
- hepatitis c virus
- mental health
- global health
- newly diagnosed
- men who have sex with men
- ejection fraction
- public health
- healthcare
- prognostic factors
- multiple sclerosis
- peritoneal dialysis
- south africa
- patient reported outcomes
- dendritic cells
- case report
- toll like receptor
- social media
- health information
- patient reported