Sex-based Differences in the Phenotypic Expression and Prognosis of Idiopathic Non-ischemic Cardiomyopathy: A Cardiovascular Magnetic Resonance Study.
Maggie MallaboneDina LabibAhmed AbdelhaleemSteven DykstraRichard B ThompsonD Ian PatersonSam K ThompsonFereshteh HasanzadehYoko MikamiSandra RivestJacqueline FlewittYuanchao FengMatthew MacdonaldMelanie KingMichael BristowLouis KolmanAndrew G HowarthCarmen P LydellRobert Jh MillerNowell M FineJames A WhitePublished in: European heart journal. Cardiovascular Imaging (2024)
In a large contemporary cohort, NICM was uniquely expressed in females versus males. Despite similar chamber dilation, females demonstrated greater concentric remodelling, lower reductions in bi-ventricular function, and a lower burden of replacement fibrosis. Overall, their prognosis remained similar to male patients with NICM.