Cell-type-specificity of isoform diversity in the developing human neocortex informs mechanisms of neurodevelopmental disorders.

Ashok PatowaryPan ZhangConnor JopsCeline K VuongXinzhu GeKangcheng HouMinsoo KimNaihua GongMichael MargolisDaniel VoXusheng WangChunyu LiuBogdan PasaniucJingyi Jessica LiMichael J GandalLuis de la Torre-Ubieta

Published in: bioRxiv : the preprint server for biology (2023)

A novel cell-specific atlas of gene isoform expression reshapes our understanding of brain development and disease.

Keyphrases

single cell
endothelial cells
poor prognosis
cell therapy
copy number
resting state
induced pluripotent stem cells
genome wide
white matter
binding protein
stem cells
mesenchymal stem cells
genome wide identification
cerebral ischemia
brain injury
genome wide analysis