Evaluating appetite/satiety hormones and eating behaviours as predictors of weight loss maintenance with GLP-1RA therapy in adolescents with severe obesity.
Megan M OberleAaron S KellyAlicia S Kunin-BatsonClaudia K FoxRebecca FreeseJustin ClarkKyle D RudserEric M BombergJustin RyderAmy C GrossPublished in: Pediatric obesity (2024)
Prior to exenatide, lower leptin response to meals was associated with improved WLM with exenatide compared to placebo. The mostly null findings of this study suggest that GLP1-RA treatment may produce similar WLM for adolescents with obesity regardless of age, BMI, sex and eating behaviours.
Keyphrases
- weight loss
- bariatric surgery
- young adults
- roux en y gastric bypass
- weight gain
- gastric bypass
- physical activity
- rheumatoid arthritis
- body mass index
- glycemic control
- disease activity
- ankylosing spondylitis
- obese patients
- early onset
- metabolic syndrome
- insulin resistance
- clinical trial
- stem cells
- randomized controlled trial
- type diabetes
- double blind
- replacement therapy
- phase iii
- study protocol
- systemic sclerosis
- mesenchymal stem cells
- idiopathic pulmonary fibrosis
- placebo controlled