Systematic evaluation of the efficacy-effectiveness gap of systemic treatments in extensive disease small cell lung cancer.

Christine M Cramer-van der WelleFranz M N H SchramelBas J M PetersJohn W G van PuttenOlaf H KlungelHarry J M GroenEwoudt M W van de Gardenull null

Published in: Pharmacoepidemiology and drug safety (2020)

OS of patients with ED SCLC treated with systemic therapy in real-world practice is 21% shorter than for patients included in trials. Age at diagnosis and performance status partly explain this gap.

Keyphrases

chronic kidney disease
end stage renal disease
small cell lung cancer
emergency department
primary care
randomized controlled trial
healthcare
newly diagnosed
systematic review
stem cells
ejection fraction
peritoneal dialysis
prognostic factors
brain metastases
smoking cessation
patient reported