Quality of Life After Deep Brain Stimulation of Pediatric Patients with Dyskinetic Cerebral Palsy: A Prospective, Single-Arm, Multicenter Study with a Subsequent Randomized Double-Blind Crossover (STIM-CP).
Anne KoyAndrea A KühnJulius HueblGerd-Helge SchneiderAnne K van RiesenMatthias EckenweilerCornelia Rensing-ZimmermannVolker Arnd CoenenJoachim K KraussAssel SaryyevaHans HartmannMartin HaeusslerJens VolkmannCordula MatthiesAnnette HornAlfons SchnitzlerJan VesperAlireza GharabaghiDaniel WeissAndrea BevotWarren MarksAngela PomykalElegast MonbaliuGuntram BorckJoerg MuellerReinhild Prinz-LangenohlTill A DembekVeerle Visser-VandewalleJochen WirthsPetra SchillerMartin HellmichLars Timmermannnull nullPublished in: Movement disorders : official journal of the Movement Disorder Society (2021)
Evidence to recommend DBS as routine treatment to improve quality of life in pediatric patients with dyskinetic cerebral palsy is not yet sufficient. Extended follow-up in larger cohorts will determine the impact of DBS further to guide treatment decisions in these often severely disabled patients. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
- cerebral palsy
- deep brain stimulation
- double blind
- placebo controlled
- parkinson disease
- obsessive compulsive disorder
- end stage renal disease
- open label
- clinical trial
- ejection fraction
- newly diagnosed
- chronic kidney disease
- phase iii
- randomized controlled trial
- prognostic factors
- combination therapy
- study protocol
- young adults