Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes.
Xiaowei ZhengSampath NarayananCheng XuSofie Eliasson AngelstigJacob GrünlerAllan ZhaoAlessandro Di ToroLuciano BernardiMassimiliano MazzonePeter CarmelietMarianna Del SoleGiancarlo SolainiElisabete A ForsbergAo ZhangKerstin BrismarTomas A SchifferNeda Rajamand EkbergIleana Ruxandra BotusanFredrik PalmSergiu-Bogdan CatrinaPublished in: eLife (2022)
This work was supported by grants from the Swedish Research Council, Stockholm County Research Council, Stockholm Regional Research Foundation, Bert von Kantzows Foundation, Swedish Society of Medicine, Kung Gustaf V:s och Drottning Victorias Frimurarestifelse, Karolinska Institute's Research Foundations, Strategic Research Programme in Diabetes, and Erling-Persson Family Foundation for S-B.C.; grants from the Swedish Research Council and Swedish Heart and Lung Foundation for T.A.S.; and ERC consolidator grant for M.M.