Patients, caregivers, and clinicians differ in performance status ratings: Implications for pediatric cancer clinical trials.
Scott H MaurerPamela S HindsBryce B ReeveJennifer W MackMolly McFatrichLi LinJanice S WithycombeShana S JacobsJustin N BakerSharon M CastellinoDavid R FreyerPublished in: Cancer (2021)
Significant differences between clinician and caregiver LPPS ratings of child performance were sustained over time; their associations with child reports were predominantly small to moderate. These data suggest that clinician-reported LPPS ratings by themselves are inadequate for determining clinical trial eligibility and should be supplemented by appropriate measures of a child's functional status reflecting the child and caregiver perspectives.
Keyphrases
- clinical trial
- mental health
- end stage renal disease
- palliative care
- newly diagnosed
- ejection fraction
- chronic kidney disease
- papillary thyroid
- emergency department
- randomized controlled trial
- electronic health record
- peritoneal dialysis
- open label
- study protocol
- machine learning
- young adults
- deep learning
- artificial intelligence
- patient reported