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The effect of intra-striatal administration of GPR55 agonist (LPI) and antagonist (ML193) on sensorimotor and motor functions in a Parkinson's disease rat model.

Iman FatemiAbbas AbdollahiAli ShamsizadehMohammad AllahtavakoliAli Roohbakhsh
Published in: Acta neuropsychiatrica (2020)
This study suggests that the striatal GPR55 is involved in the control of motor functions. However, considering the similar effects of GPR55 agonist and antagonist, it may be concluded that this receptor has a modulatory role in the control of motor deficits in an experimental model of Parkinson.
Keyphrases
  • functional connectivity
  • fatty acid
  • parkinson disease
  • traumatic brain injury
  • binding protein